All of Andrew Dickson's Comments + Replies

Nice post Ryan! This kind of modeling strikes me as a very useful exercise, despite the fact that reasoning about systems of conditional probabilities based on conditions with complex descriptions at this scale is a little clunky for our human brains.

Regardless of the final estimates of P(scheming), which are likely to have high uncertainty, I also see a lot of value in the list of predictive factors you have called out here and their relative magnitude. If nothing else, these factors can help us by serving as warning signs or signs that things are going i... (read more)

I very much agree with this concern and I think that synthetic biology can be a good comparable case to ground our intuitions and help estimate reasonable priors.

For years, researchers have been sounding the alarm around the risks of advanced biotech, especially around tools that allow gene synthesis and editing. And then we had Covid-19, a virus that regardless of the politicization, probably was created in a lab. And in any case, regardless of whether you believe it was or wasn't it seems clear that it easily could have been. Worse, it's clear that somet... (read more)